Tewis Bouwmeester is Senior Unit Head in the Department of Developmental and Molecular Pathways (DMP) at the Novartis Institutes for Biomedical Research (NIBR) in Basel. He is a trained developmental biologist working in the field of regenerative medicine. His group is part of a regenerative medicine initiative to identify low molecular weight compounds and/or secreted factors that can activate adult tissue stem/progenitor cells such as intestinal crypt cells and hematopoietic precursors to regenerate damaged and/or aged tissues. In addition, he has an interest in dissecting the mechanisms of lineage restriction by identifying compounds (stem cell differentiators) that can drive embryonic stem cells into a defined somatic lineage. His group has core expertise in “state of the art” quantitative proteomics technologies to: i) dissect regulatory protein-protein interactions in vivo, ii) identify and quantify post translational modifications such as phosphorylation and iii) to monitor global proteome changes in response to growth factors and/or upon lineage commitment.

For detail and recent publications: https://www.novartis.com/our-science/postdoc-program/research-themes/regenerative-medicine/tewis-bouwmeester-phd